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pietillidie 



Joined: 07 Jan 2005


PostPosted: Thu Feb 01, 2024 12:47 am
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What'sinaname wrote:
Godfrey's has gone into administration.

Not surprising and I am surprised they still exist. Not sure how a stand alone vacuum retailer could survive.

I'd suggest 90% of people buy the following vacuums (not in order):
Dyson
Robovac
Kmart

Yeah, it's astonishing how long they lasted. I guess they must've diversified into other stuff after I left Oz if they lasted that long, but good machines don't really need to come with much advice and personal service.

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What'sinaname Libra



Joined: 29 May 2010
Location: Living rent free

PostPosted: Thu Feb 01, 2024 6:34 am
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^ correlates with the decline in bowling. I guess there are fewer people that need to vacuum a 16 pound bowling ball.
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Skids Cancer

Quitting drinking will be one of the best choices you make in your life.


Joined: 11 Sep 2007
Location: Joined 3/6/02 . Member #175

PostPosted: Thu Feb 01, 2024 1:59 pm
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A few weeks ago, when the powerball jackpot had just hit the $100 million, I had this vivid dream that I bought the winning ticket from Belmont Forum shopping centre. The place is miles away from my house now, I did grow up not far from there, but hadn't been near the place for 30 years.
Been there 3 times in the last 3 weeks Laughing . This time it was to buy $2600 worth of systems and powerpicks for a syndicate of 26 of us at work.

I drove a different way today, thought (wrongly) I'd avoid the morning traffic.

Anyway, i stopped at a set of lights in Morley, right next to a house that brought back memories.
Greg lived there in the 80's. He was an apprentice chippie for the same maintenance company I was completing my plumbing apprenticeship at, there was a dozen of us young blokes doing different trades.
He was part of a team, fondly dubbed the A Team, who used to do daily rounds of multiple institutions in the Perth metro carrying out routine maintenance tasks - fix; doors & windows, painting, gardening etc.
It wasn't long before the company worked out that after the A team had visited, items were going missing. A trap was laid and Greg was busted at home, in the shower, trying to scrub the ink off his hands that had been planted on some cash.
He wasn't a 'bad' bloke, young and stupid maybe. I wondered how that fatal error, which saw him immediately fired, effected the rest of his life. I never saw him or heard of him again.

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nomadjack 



Joined: 27 Apr 2006
Location: Essendon

PostPosted: Fri Feb 02, 2024 10:14 am
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pietillidie wrote:
What'sinaname wrote:
Godfrey's has gone into administration.

Not surprising and I am surprised they still exist. Not sure how a stand alone vacuum retailer could survive.

I'd suggest 90% of people buy the following vacuums (not in order):
Dyson
Robovac
Kmart

Yeah, it's astonishing how long they lasted. I guess they must've diversified into other stuff after I left Oz if they lasted that long, but good machines don't really need to come with much advice and personal service.


My wife and i will need to find a new 'life is actually pretty good' reference point...Whenever we used to get bored with our own work, we'd note 'things could be worse...we could be working at godfreys'. I can't imagine anything more soul-destroying. The few times we shopped there the shop assistants looked a hair's breadth away from topping themselves... Shocked
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David Libra

I dare you to try


Joined: 27 Jul 2003
Location: Andromeda

PostPosted: Mon Feb 05, 2024 5:18 pm
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I know stuff like this happens all the time (and particularly in America), but here's another frankly jaw-dropping account of police entrapment – in which secret agents more or less encourage a target to plan terrorist acts and then arrest them for it – from Australia:

https://www.theguardian.com/australia-news/2024/feb/03/australian-undercover-police-autistic-13-year-old-fixation-islamic-state

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Skids Cancer

Quitting drinking will be one of the best choices you make in your life.


Joined: 11 Sep 2007
Location: Joined 3/6/02 . Member #175

PostPosted: Tue Feb 06, 2024 9:20 pm
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Just updating one of the daughters cars. Picked up a nice cx5 diesel for a fair price. I hadn't been near a car yard for years.

Back in the early 90's I had a bit of a financial windfall and enjoyed a few months off work. When I decided to get back to work, a relative with a car yard talked me into selling cars. It was a shit job, I lasted about 12 weeks. But I did see some funny things.

Early one Saturday these two old Italian gents rock in. Looked like local market gardeners in their overalls. They drive a few cars and the salesman sold them a V8 WB one tonner. A few days go by, nothing happening, the salesman starts chasing things up.
These two gentleman had been driving around, buying cars everywhere! They'd actually put small deposits on 9 cars in a fortnight. The sales mobs got a bit stroppy, signed contracts etc. But soon backed off when they became aware that, one of the gents sons, was a high up gangster of some clan.

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Culprit Cancer



Joined: 06 Feb 2003
Location: Port Melbourne

PostPosted: Wed Feb 07, 2024 4:50 pm
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^^ Funny thing, my late brother worked at a Car Yard run by the Mafia. Used to get good deals. On weekends when they were opened they had a few escorts (I don't mean the cars) visit regularly. Some nice sales went down with added incentives. Shocked Very Happy : Laughing Laughing
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What'sinaname Libra



Joined: 29 May 2010
Location: Living rent free

PostPosted: Thu Feb 08, 2024 4:20 pm
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Will we see another light sentence for a woman raping a boy?

https://www.news.com.au/world/north-america/married-teacher-admits-to-sneaking-into-14yearold-students-home-to-have-sex-in-his-bed/news-story/0c95733b1346cd6a1eb495cea9617ce0

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roar 



Joined: 01 Sep 2004


PostPosted: Sat Feb 10, 2024 9:32 am
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Hope so.
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What'sinaname Libra



Joined: 29 May 2010
Location: Living rent free

PostPosted: Sat Feb 10, 2024 3:50 pm
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Chernobyl might have been the best thing to happen now that we can study wolves genome that prevents cancer.
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Jezza Taurus

2023 PREMIERS!


Joined: 06 Sep 2010
Location: Ponsford End

PostPosted: Sat Feb 10, 2024 10:39 pm
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What'sinaname wrote:
Chernobyl might have been the best thing to happen now that we can study wolves genome that prevents cancer.

Yes, very interesting.

Quote:
Chernobyl wolves have evolved resistance to cancer

A recently released study has shed light on the extraordinary genetic adaptations of wolves within the Chernobyl Exclusion Zone (CEZ).

The experts found that wolves in Chernobyl have genetically altered immune systems and some level of resistance to cancer. This discovery offers invaluable insights into the mechanisms of survival in one of the world’s most hostile environments.


https://www.earth.com/news/chernobyl-wolves-have-evolved-resistance-to-cancer/

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pietillidie 



Joined: 07 Jan 2005


PostPosted: Mon Feb 12, 2024 7:03 am
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^Nice find, and quality researchers by the looks.

There has also been quite a lot of recent work using viruses to attack cancer (e.g., https://www.cancer.gov/news-events/cancer-currents-blog/2023/oncolytic-virus-blocking-tgf-beta ).

As a replication problem, nailing cancer has always been inherently dependent on us better understanding the fundamentals, such as genes and viruses, and having something like machine learning to crack the code. Here's hoping we're set for a breakthrough.

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pietillidie 



Joined: 07 Jan 2005


PostPosted: Mon Feb 12, 2024 7:12 am
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^The posts above on car yards and the mafia somehow reminded me of an Aussie movie I'd forgotten about but loved as a teenager: The Big Steal.

I'm scared of watching it again because they're never as good as I remember!

https://www.youtube.com/watch?v=ZF4zsEsAVl4

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stui magpie Gemini

Prepare for the worst, hope for the best.


Joined: 03 May 2005
Location: In flagrante delicto

PostPosted: Mon Feb 12, 2024 10:18 am
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Jezza wrote:
What'sinaname wrote:
Chernobyl might have been the best thing to happen now that we can study wolves genome that prevents cancer.

Yes, very interesting.

Quote:
Chernobyl wolves have evolved resistance to cancer

A recently released study has shed light on the extraordinary genetic adaptations of wolves within the Chernobyl Exclusion Zone (CEZ).

The experts found that wolves in Chernobyl have genetically altered immune systems and some level of resistance to cancer. This discovery offers invaluable insights into the mechanisms of survival in one of the world’s most hostile environments.


https://www.earth.com/news/chernobyl-wolves-have-evolved-resistance-to-cancer/


It is an interesting read. How it could be used to help Humans is hard to figure out, wolves obviously breed a lot faster than people, they can go through 10 generations before humans are on the second so in nearly 40 years the current population of Wolves is basically 20 generations on from when Chernobyl happened.

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pietillidie 



Joined: 07 Jan 2005


PostPosted: Mon Feb 12, 2024 3:54 pm
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^It's the mechanics of the change that's the opportunity. They know canine genes pretty well, so they can study changed and unchanged populations, try to isolate the protective change, and see if they can simulate it (artificially and experimentally, not through decades of breeding), or at least learn from it. The genetic overlap between mammals is huge, so it's like a giant natural experiment that no one needs ethical approval and tens or hundreds of millions of dollars to conduct. And cancer's cancer — a cell DNA replication error — whatever the species.

It's hard to fathom, but very small differences result in very different species. Here's an article from several years ago:

Quote:
"The genetic difference between humans and dogs is quite small," said Dr. Rodney Page, professor of medical oncology and director of the Flint Animal Cancer Center. "Humans and dogs are 95 percent identical genetically — and the diseases that affect humans including breast cancer, prostate cancer, and melanoma are almost identical."

In fact, cancer is so common in dogs that doctors are studying them as a model for treating the disease in humans.

Comparative oncology, a new field that integrates cancers seen in veterinary patients into more general studies of cancer biology and therapy, studies the similarities between naturally occurring cancers in pets and cancers in people — in hopes that our genetic similarities can provide clues to treat cancer more effectively.

Doctors estimate that there are 400 to 500 diseases that are genetically identical between dogs and humans.

https://www.nbcnews.com/health/cancer/genetic-similarities-between-dogs-people-are-helping-cancer-research-n841556

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Last edited by pietillidie on Mon Feb 12, 2024 4:07 pm; edited 2 times in total
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